Summary of the Systematic Review

Article Citation

Outcomes of Cochlear Implantation in Patients With Post-Meningitis Deafness: A Systematic Review and Narrative Synthesis

Singhal, K., Singhal, J., et al. (2020).
Journal of International Advanced Otology, 16(3), 395-410.
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Indicators of Review Quality

  • Yes The review states a clearly focused question/aim.
  • Yes Criteria for inclusion of studies are provided.
  • No Search strategy described in sufficient detail for replication.
  • Yes Included studies are assessed for study quality.
  • Yes Quality assessments are reproducible.
  • Yes Characteristics of the included studies are provided.

Article Details

Description

This is a systematic review of studies investigating cochlear implantation outcomes in patients with post-meningitis deafness.

Questions/Aims Addressed

The aim of this review is to "summarize outcomes following cochlear implantation (CI) in patients with post-meningitis deafness" (p. 395).

Population

Children or adults with post-meningitis deafness

Intervention/Assessment

Cochlear implantation

Number of Studies Included

19

Years Included

Not stated


Conclusions from This Systematic Review

What are Conclusions?

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Treatment

For patients with post-meningitis deafness, cochlear implantation (CI) was found to improve auditory, speech perception, and speech intelligibility/production outcomes. Post-CI audiometric outcomes of post-meningitis patients were comparable to CI patients deafened by other causes. While post-meningitis patients with labyrinthitis ossificans (LO) demonstrated poorer post-CI outcomes compared to patients with patent cochlea, patients with LO still achieved significant improvement from CI.  Patients with comorbid neurological sequalae exhibited delayed improvements with slower acquisition of speech perception, and they required additional follow-up and auditory training. The individual patient's outcomes were also dependent on the duration of deafness pre-CI and the depth of electrode insertion. Patients demonstrating the best post-CI outcomes had no other neurological sequalae, little to no ossification of their cochlea, a shorter duration of deafness, and received full electrode insertion. Due to the variability of ossification and hearing recovery post-meningitis and the challenges of pre-operative imaging, further research on the timing of CI is needed.

Keywords: Cochlear Implants, Cochlear Implants, Devices, Cochlear Implants, Comorbid Diseases and Disorders, Infectious Diseases (e.g. Cytomegalovirus/Meningitis), Comorbid Diseases and Disorders, Comorbid Diseases and Disorders, Devices, Risk Factors, Risk Factors, Infectious Diseases (e.g. Cytomegalovirus/Meningitis), Infectious Diseases (e.g. Meningitis), Devices

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Treatment

For patients with post-meningitis deafness, cochlear implantation (CI) was found to improve auditory, speech perception, and speech intelligibility/production outcomes. Post-CI audiometric outcomes of post-meningitis patients were comparable to CI patients deafened by other causes. While post-meningitis patients with labyrinthitis ossificans (LO) demonstrated poorer post-CI outcomes compared to patients with patent cochlea, patients with LO still achieved significant improvement from CI.  Patients with comorbid neurological sequalae exhibited delayed improvements with slower acquisition of speech perception, and they required additional follow-up and auditory training. The individual patient's outcomes were also dependent on the duration of deafness pre-CI and the depth of electrode insertion. Patients demonstrating the best post-CI outcomes had no other neurological sequalae, little to no ossification of their cochlea, a shorter duration of deafness, and received full electrode insertion. Due to the variability of ossification and hearing recovery post-meningitis and the challenges of pre-operative imaging, further research on the timing of CI is needed.

Keywords: Cochlear Implants, Cochlear Implants, Devices, Cochlear Implants, Comorbid Diseases and Disorders, Infectious Diseases (e.g. Cytomegalovirus/Meningitis), Comorbid Diseases and Disorders, Comorbid Diseases and Disorders, Devices, Risk Factors, Risk Factors, Infectious Diseases (e.g. Cytomegalovirus/Meningitis), Infectious Diseases (e.g. Meningitis), Devices

Go to Map

Treatment

For patients with post-meningitis deafness, cochlear implantation (CI) was found to improve auditory, speech perception, and speech intelligibility/production outcomes. Post-CI audiometric outcomes of post-meningitis patients were comparable to CI patients deafened by other causes. While post-meningitis patients with labyrinthitis ossificans (LO) demonstrated poorer post-CI outcomes compared to patients with patent cochlea, patients with LO still achieved significant improvement from CI.  Patients with comorbid neurological sequalae exhibited delayed improvements with slower acquisition of speech perception, and they required additional follow-up and auditory training. The individual patient's outcomes were also dependent on the duration of deafness pre-CI and the depth of electrode insertion. Patients demonstrating the best post-CI outcomes had no other neurological sequalae, little to no ossification of their cochlea, a shorter duration of deafness, and received full electrode insertion. Due to the variability of ossification and hearing recovery post-meningitis and the challenges of pre-operative imaging, further research on the timing of CI is needed.

Keywords: Cochlear Implants, Cochlear Implants, Devices, Cochlear Implants, Comorbid Diseases and Disorders, Infectious Diseases (e.g. Cytomegalovirus/Meningitis), Comorbid Diseases and Disorders, Comorbid Diseases and Disorders, Devices, Risk Factors, Risk Factors, Infectious Diseases (e.g. Cytomegalovirus/Meningitis), Infectious Diseases (e.g. Meningitis), Devices

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