Summary of the Systematic Review

Article Citation

Meta-Analysis on the Rate of Pharyngocutaneous Fistula in Early Oral Feeding in Laryngectomy Patients

Singh, R., Karantanis, W., et al. (2021).
American Journal of Otolaryngology, 42(1), 102748.
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Sponsoring Body

Not stated

Article Quality Ratings

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Indicators of Review Quality

  • Yes The review states a clearly focused question/aim.
  • Yes Criteria for inclusion of studies are provided.
  • Yes Search strategy described in sufficient detail for replication.
  • Yes Included studies are assessed for study quality.
  • No Quality assessments are reproducible.
  • Yes Characteristics of the included studies are provided.

Article Details

Description

This is a systematic review and meta-analysis of retrospective and prospective studies investigating the rate of pharyngocutaneous fistula following early oral feeding in patients who have undergone a laryngectomy.

Questions/Aims Addressed

The primary aim was to estimate the risk of developing pharyngocutaneous fistula in laryngectomy patients undergoing early oral feeding.

Population

Patients following laryngectomy

Intervention/Assessment

Early oral feeding 

Number of Studies Included

12

Years Included

1990 up to January 1, 2020


Conclusions from This Systematic Review

What are Conclusions?

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Treatment

Although individual studies included in the meta-analysis did not demonstrate a significant difference between early and late oral feeding in the development of pharyngocutaneous fistula (PCF), the overall meta-analysis demonstrated an increased relative risk (RR = 1.5) for developing PCF following early oral feeding after laryngectomy.

Keywords: Timing, Adults, Timing (e.g. Pre-/Post-Cancer Treatment), Age, Cancer Treatment Received (Laryngectomy/Chemotherapy), Post-Cancer Treatment, Laryngectomy, Swallowing, Head and Neck Cancer

Service Delivery

Although individual studies included in the meta-analysis did not demonstrate a significant difference between early and late oral feeding in the development of pharyngocutaneous fistula (PCF), the overall meta-analysis demonstrated an increased relative risk (RR = 1.5) for developing PCF following early oral feeding after laryngectomy.

Keywords: Timing, Adults, Timing (e.g. Pre-/Post-Cancer Treatment), Age, Cancer Treatment Received (Laryngectomy/Chemotherapy), Post-Cancer Treatment, Laryngectomy, Swallowing, Head and Neck Cancer

Go to Map

Treatment

Although individual studies included in the meta-analysis did not demonstrate a significant difference between early and late oral feeding in the development of pharyngocutaneous fistula (PCF), the overall meta-analysis demonstrated an increased relative risk (RR = 1.5) for developing PCF following early oral feeding after laryngectomy.

Keywords: Timing, Adults, Timing (e.g. Pre-/Post-Cancer Treatment), Age, Cancer Treatment Received (Laryngectomy/Chemotherapy), Post-Cancer Treatment, Laryngectomy, Swallowing, Head and Neck Cancer

Service Delivery

Although individual studies included in the meta-analysis did not demonstrate a significant difference between early and late oral feeding in the development of pharyngocutaneous fistula (PCF), the overall meta-analysis demonstrated an increased relative risk (RR = 1.5) for developing PCF following early oral feeding after laryngectomy.

Keywords: Timing, Adults, Timing (e.g. Pre-/Post-Cancer Treatment), Age, Cancer Treatment Received (Laryngectomy/Chemotherapy), Post-Cancer Treatment, Laryngectomy, Swallowing, Head and Neck Cancer

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